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“Many people praise and acknowledge the healing power of plants, but few people actually take action to prevent their extension by planting and conserving them for future generations.” (Ernest Rukangira )

Thursday, 26 December 2013

MEDICINAL PLANTS AND PATENTS BY PROFESSOR G. L. CHAVUNDUKA PRESIDENT: ZIMBABWE NATIONAL TRADITIONAL HEALERS ASSOCIATION (ZINATHA)


More than 500 different types of plants are used for medicinal purposes in Zimbabwe. These traditional medicines are used by many people every day. About 80% of the people in the country use these plant medicines at some stage of their illness. This consumption of indigenous medicine is likely to remain at current levels in the future largely because there is a wide range of illnesses and needs which cannot be adequately treated by western medicine. Plant medicine is infact a basic consumer good essential for the welfare of most African households. The supply of plant products is not only critical for the welfare of millions of people who use them but also critical for the welfare of people employed in this sector. There are about 50,000 registered traditional health practitioners in Zimbabwe. They derive their income from harvesting, preparation and the sale of medicinal plants, and they also attend to patients. Besides the 50,000 professional healers, there are also hundreds of traders who derive much of their income from selling indigenous medicinal plants at the various urban markets. The medicinal plant industry, therefore, plays a critical role in empowering large numbers of people. The traditional health sector is an important segment of the Zimbabwean society in another way. It is estimated that around 4,000 tons of plant material with a value of Z$150m is used annually for medical purposes.

But the country is slowly losing some of these valuable medicinal plants and medical knowledge. Besides the destruction of forests our traditional healers have been victims of exploitation of their knowledge and medicines since the beginning of this century. Exploitation of the knowledge and medicines of traditional healers takes various forms. Many academics interview traditional healers and publish the results of such interviews without acknowledging the source of much of the information. Some modern medical scientists also interview and even observe traditional healers at work and then pass on the results of their investigations to established pharmaceutical companies. Traditional healers are also aware that many agents of foreign governments, pharmaceutical companies and research organizations have been coming into the country to collect specimens from traditional healers which they screen for specified biological activity at home then isolate active compounds and apply for patents for these active compounds. Traditional healers do not receive any form of compensation although a few tradition healers are known to have agreed to sell off their knowledge and resources for a few hundred dollars. Thus, many medical scientists here and abroad seek access to our traditional knowledge for the primary purpose of developing more profitable products. Once healers share this information, they lose control over that knowledge. Moreover, if the material is eventually patented, access to this material can be legally restricted by monopoly patents.

The long-term consequences of the present trend are clear, as listed below:
a.)Thousands of traditional healers will loose their major source of income, they will become unemployed,
b.)Many medicinal plant traders will be squeezed out to this indigenous market,
c.)Many households will loose access to their basic consumer good,
d.)Bio diversity and health care will be negatively impacted,
e.)The declining supply of indigenous medicinal plants will generate significant economic losses to the country.
Obtaining patents for our inventions appears to be a step in the right direction. With respect to plants, the following parts used in traditional medicine: roots, leaves, bark, whole plant, tuber, fruits, bulb, seeds, latex, stem, fiber, rhizome, twigs, pod, flowers, sap, wood, cob, grain and branches. ZINATHA decided to try and isolate pure compounds from some of these plant medicines and have the compound, where possible, patented. This involves extraction and purification of active agents from some of these medicinal plants. A number of pure compounds from some of our medicinal plants have already been isolated. We have obtained a patent for the treatment of HIV/AIDS. We will, in the near future, conduct formal clinical trials in order to understand the full medicinal value of the compound. It is our hope that if the results are encouraging, commercialization of the drug will begin. This has been our first attempt. There were a number of issues to be discussed and resolved before proceeding to the patenting stage. Firstly, it was decided that the process leading to the patenting of a particular compound from the field of traditional medicine should be the responsibility of ZINATHA in collaboration with other bodies, if necessary, rather than that of an individual healer. There are two main reasons for this. One important reason is that a substantial majority of plant medicines used by one healer are also used, often for the same purposes, by another healer. Where this was the case, it was felt that all traditional health practitioners have a right collectively, through their organization, to benefit from their traditions and genius. The question of how the potential income arising from such discoveries might be distributed is, in this case, largely resolved by making the Association, the beneficiary or one of the main beneficiaries of the invention. In the event of any conflicts, the Association is the obvious imbalance of the financial power and legal expertise that would arise between a single traditional healer and interested multinational corporations. Apart from huge amounts of money required for the necessary research and legal fees, a single healer would have to negotiate alone with a number of specialists and institutions would be riddled with loopholes, legal and technical jargon aimed at weakening the position of the healer further. There are no effective mechanisms in place to ensure fair and equitable sharing of the benefits.

The process leading to patenting has been expensive and complex. ZINATHA could not do it alone and needed assistance. The Association needed laboratories where the various tests could be carried out. Extraction and purification of active agents were carried out at the University of Zimbabwe. Screening was done at the National Cancer Institute in the USA, through the provisions of an agreement between ZINATHA and the Institute. ZINATHA and the University of Zimbabwe will be the main beneficiaries of the invention if the project is successful.
There are many plant medicines that will be difficult to fit into the patent option that I have described. Many traditional remedies are complex; several plants might be cooked with various portions of animals, birds, fish, snakes and insects. Another problem is that mixtures used by traditional healers are not always intended to eliminate the symptoms alone. Some of the ingredients are intended to suppress the toxic effects of the other drugs. This enables the body to with stand the aggressive nature of the drugs. Furthermore, some poisonous plants are used as medicine. Traditional healers are aware of toxicity. They know which plants are poisonous and which ones are not. They also know that some plants may be toxic at one stage of their growth and comparatively innocuous at another stage. Some poisonous plants become good medicines at some stages of their growth, or during certain seasons of the year. It also appears to us that a drug developed from a compound of a particular medicinal plant may not, in certain cases, be as effective as using the whole root, leaves, or bark of the original plant. Therefore, natural medicines should continue to have a place in health care.

Paper read at: National Workshop on the Development of Sui-Generis Legislation on Intellectual Property Rights (IPR) - Patents for Zimbabwe, Kadoma Ranch Motel Conference Centre, 6-10 September, 1998

At this point, the Manila Declaration concerning the Ethical Utilization of Asian biological Resources (Appendix 3.3) developed at the Seventh Asian Symposium on Medicinal Plants and Species and other Natural Products (ASOMPS VII) held in Manila in 1992, deserve special mention. The declaration incorporates a suggested code of ethics for foreign plant collectors and proposed set of contract guidelines for use by source countries in agreement with appropriate source country organizations as opposed to individuals of the country, and the contract guidelines suggest minimum standards related to, for example sample size, sale of extracts, royalty shares, and exclusivity limits (Baker et al., 1995).

*The amount of material collected for initial screening should not normally exceed 100-150g (dry weight) unless specific permission is obtained.

*Payment should include all handling expenses.

*Where screening is carried out with the aid of a partner organization, for example,National Cancer Institute, USA, in the developed world, a minimum of 60% of any income arising from the supply of extracts to commercial organizations should be returned to the appropriate country organization, such as ZINATHA.

* The country organization should receive a minimum of 51% of any royalties arising from external collaboration that result in marketable products. As fair royalties are normally 3-5% the national organization would expect to receive a minimum royalty of 1.5-2.5%

*The country organization should not sign any agreement that gives indefinite exclusive rights to any external party. Exclusivity should be limited to no more than two-year periods.

*Complete evaluation results should be reported to the supplying country within 6-9 months.

*If there is a threat of destructive harvesting, costs of sustainable harvesting or development of alternative supplies must be borne by the external organization.

*The contribution of research participants should be recognized through co-authorship of publications.
* Where possible, screening of extracts should be carried out it the country of origin and assistance should be provided to develop this expertise wherever possible.
*Agreement on patents should be reached between different parties.

Such a contract is a more effective device as laws lack extra-territorial effect. On the other hand, a breach is usually enforceable as countries provide for reciprocal enforcement. In respect of those countries where no such mutually enforceable mechanisms exist, the legal provisions require the licenses to deposit a sum sufficient to cover any potential damages for non-compliance. Additionally, or in lieu of this deposit, the licensee may be required to obtain an agreement from his or her government to indemnify the country whose resources is sought for any loss arising from a breach of the agreement.

Ultimately, it will be necessary to set up a multilateral regime that can then oversee and enforce obligations undertaken.

In conclusion, it is quite clear that until recently, the prevailing attitude in developed nations regarded the world's genetic resources, which are mainly concentrated in the developed world, as a common resource of human kind, to be exploited freely irrespective of national origin. With the devastation being wreaked in the tropical forests the resurgence in interest in recent years in the discovery of novel drugs from natural sources, particularly plants, the Zimbabwean scientific community has realized that the conservation of the Zimbabwean genetic resources and the indigenous knowledge associated with their use are of primary importance if their potential is to be fully explored. With this realization has come a recognition that these goals must be achieved through collaboration with, and fair and equitable compensation of, the Zimbabwean scientist, traditional healer and the communities.

Appendix 3.1

TRIPS - Trade-Related Intellectual Property

Every country should have minimum standard form of Intellectual Property. TRIPS as agreed by most countries lays down basic principles, specific rules for various rights, and rules on enforcement of rights, on maintaining rights, and on transitional arrangements.

The guiding principles

*All member countries must treat nationals or other member countries as they treat their own, without any discrimination.
* Intellectual Property should contribute to innovation, to transfer of technology, to social and economic welfare and to a balance of rights and obligations.

Patents

*Inventions in all fields of technology, except:
- methods for curing humans and animals
- plants and animals, and essentially biological processes for producing them - micro organisms and microbiological processes
- plants varieties, must be protected by patents

An effective sui generis system can be used to protect some plant varieties.

Patent Rights
Minimum rights for patentees are laid down in the Zimbabwean law, Patent Act of 1971 [Chapter 26:03] Revised Edition 1996. The Act stipulates three criteria for patentability. These are novelty, an inventive step and industrial application. It excludes from patentability animal plant variety.
For process patents, the burden of proof must be shifted to accised infringers in at least one of two cases:
*If the product of the process is new or
*If the owner of the patent cannot show what process was actually used, but it is likely that the patent process was used.

Patent Enforcement
Detailed provisions are intended to make it easier to enforce IP rights. Remedies must include damages and injunctions against further infringement, including interim injunctions to preserve the patentee's rights until trial. However, criminal penalties are only required for serious trademark of copyright counterfeiting.

Transitional Arrangement

Equal treatment comes into effect everywhere on signing. Other provisions must be introduced within 1 year, except for developing countries (5 years). Developing countries like Zimbabwe may also delay the extension of patent rights to new areas of technology for a further 5 years. Least developed countries need not change their laws for 10 years and may seek further extensions, if required.

Independently of the foregoing, the patentability of plants and animals to be reviewed 4 years after the agreement comes into force.

Parties are required to provide incentives for transfer of technology to least-developed countries and to provide (when requested and on agreed terms) technical financial co-operation to developing countries on IP matters.

Patents on Plants

Preamble

Intellectual Property Rights are justified, in part, as human right and in part as a contract or bargain with the public. The originator gives to the public something new that it would not otherwise have had. This could, for example, be a process to produce highly active products from Phytolacca dodecandra. In return, the public gives to the originator limited rights n the "new thing" for a limited period. The originator is rewarded by exploiting these rights in person, or allowing others to exploit them for a fee.

The reward is always self-regulating, if for example the price is set too high or the public is simply not interested in the invention.

For the system to work the following assumptions have to be made:
* A market economy,
* Appropriate scope and term of rights awarded, and
* Careful fulfillment of the conditions imposed on grant.
Many countries in the developed world are now granting patents on life forms and on constituents of life forms, such as DNA sequences and cell lines.
A patent is only granted when the invention is new. The originator must be inventive and be in a position to describe to others how to make use of his/her invention. A patent must enhance what people have always been doing and is granted for an invention and not discovery. The distinction must be made.
* A discovery is new knowledge
* An invention is new process or product.

This distinction is important to keep in mind when considering how genes may be patented. The sequence of a gene is a discovery, pure and simple. It is knowledge about something that already exists. However, it may enable new things to be produced, and these may in principle be patented.

Genes

These are the fundamental physical and functional unit of heredity; the portion of a DNA molecule that is made up of an ordered sequence of nucleotide based pairs that produce a specific product or have an assigned function. They cannot be patented. They already exist and are therefore not new. They can only be discovered and not invented. What is patented is not the gene as such but the gene isolated from its natural surroundings and products containing this isolated gene. Gene inventions of this sort will be patented under TRIPS.

Plant Cells

These will also be patented under TRIPS if the new plant cells contain transformed DNA. Patents on plants are granted, provided they do not meet the Union of the Protection of New Varieties of Plants (UPOV) criteria for varieties. TRIPS does not require patents on plants, provided plants varieties can be protected by "sui generis system" for example UPOV. Zimbabwe is currently looking into the development of sui generis legislation.
The European Patent Convention provides that "essentially biological processes" and their products are not patentable. "Microbiological Processes" (and their products) however, are patentable. Plants obtained by conventional breeding are not patentable, but plants modified by gene technology are.

In the United States, there is no bar on patenting plants in any form, or breeding processes. In consequence, patents are granted on plant varieties produced by conventional breeding.

The Manila Declaration

Developed at the Seventh Asian Symposium on Medicinal Plants and Spice, and other Natural Products (ASOMPS VII) which was held in Manila, Philippines from February 2 - 7, 1992 and was attended by 280 scientists from 37 countries.

Given that:
* The Maintenance of biological and cultural diversity is global concern,
* Developing countries are major centres of biological and cultural diversity,
* There is increased interest in biological material with medicinal and other economic values,
* Indigenous peoples frequently possess knowledge that provides a key to natural products of economic value.

Recognizing that:
* All national governments have sovereignty over their biological resources,
* Current practices of exploitation of biological resources and indigenous knowledge are frequently inequitable, favoring technologically advanced organizations often based in developed countries, to the disadvantage of both conservation and development in the country of origin,

* Their is need for further investment in training and technology in developing countries and for equitable partnerships with countries in order to obtain new products from biological material.

* There has been insufficient acknowledgement of the essential roles that indigenous knowledge (i.e. intellectual property) play in identifying important natural products.

Thus it recommended that:
* National governments, with advice from appropriate professional organizations within the region, develop adequate legislation to exercise control over collection and export of biological material,

* As a high priority, governments, international agencies, multinational corporations and academic institutions, through training, laboratory construction and technology transfer, should support the development of human and material resources needed for all aspects of local biological evaluations of indigenous materials for conservation and for managed development,

* For all collecting, the authorizing agreement(s) should include provision for any subsequent commercial development that may eventually arise,

* Internationally recognized professional societies develop a code of ethics that facilitates the development of equitable partnership in the development of new natural products from biological material,

* Mandatory royalty or license agreement be established to ensure fair and equitable distribution of benefits to the region of origin,

* Supply agreements should only be made by the appropriate country organization and not with individuals within that country,

* In order to avoid over - exploitation of promising species, the country organization should adopt methods to protect the identity and provenance of its biological material,

* Specific regulations be established to ensure that the collection and export of biological materials is adequately monitored and controlled in the interest of the country supplying the material. These should include the requirement that:
- Collections are made together with local counterparts appointed by the country organization involved,
- Adequate annotated, preserved voucher specimens of biological material are lodged in appropriate national institutions,
- Sufficient funds are provided by external organization to cover the support costs that may be incurred,
- If there is a threat of destructive harvesting, provision must be made for sustainable or development of alternative supplies,

- The traditional knowledge of local participants contributing to development of new natural products must be recognized as significant intellectual property.

REFERENCES

Baker, J.T., Morris R.T., Carte B., Cordell, G.A., Soejarto, D.D. et al 1995. Natural Product Drug Discovery and Development: New Perspective on International Collaboration. J. Natural Product, 58(9): 1325 - 1357

Balick, M. 1990 Ethnology and the Identification of Therapeutic Agents from the Rainforest, In D.J. Chadwick and J. Arsh, eds, Bioactive Compounds from Plants.

Croom, Jr., E.M. 1983. Documenting and Evaluating Herbal Remedies. Economic Botany. 37: 13-27.

Fransworth, N., et al. 1985 Medicinal Plants in Therapy. WHO Bulletin, 63, 965 - 966

Munasinghe, M. (1992) Bio diversity Protection Policy: Environmental Valuation and Distribution Issues.

Ndamba, J., Nyazema, N.Z. Anderson, C., Makaza, N. and Kaoendera, K.C. 1994. Traditional Remedies Used in the Treatment of Urinary Schistosomiasis in Zimbabwe, J. Ethnopharmacology 42: 125-132

Ndamba, J., Nyazema, N.Z. Anderson, C., Makaza, N. and Kaoendera, K.C. 1994. The Doctrine of Signatures and Similitudes: A Comparison of the Efficacy of Praziquantel and Traditional Herbal Remedies Used in the Treatment of Urinary Schistosomiasis in Zimbabwe. Int. J. Ethnopharmacology 32: 142-148.

Posey, D. (1990a) Intellectual Property Rights: What is the position of ethnobiology? J. Ethnobiology 10, 93-98.

Ehrlich, P.R. and Ehrlich, A.H. (1992) The value of biodiversity. Ambio 21, 219-226

Zimbabwe Patents Act. Chapter 26:03. Revised Edition, 1996. Government Printer, Harare, pp74
Reply


To anyone who can help with advice or recommend S A contacts,

I would very much like to ask anyone in the Phytomedica group if
there is anyone in South Africa who could help us with testing our
IMITHI remedies AS THEY ARE for efficacy - as antibacterial,
antifungal and also anti-inflammatory. OR if anyone else has
managed to get tests done with whole plant remedies.

It does not seem relevant to test the individual plant ingredients in
the conventional Western microbiological way by separating,
using various solvents and drying methods, crushing, centrifuging
etc. etc. to isolate single chemical components which might have
these actions.

This is not the way traditional plant based remedies are ever
prepared or used by the people who need them and use them. We
need the whole plant mixtures, powders, decoctions, tinctures and
ointments etc., tested in a laboratory, for things like zones of
inhibition with bacteria and fungus etc. which I know can be done.

These tests and methodolgies seem not to be used or accepted
by "scientific" bodies and researchers at academic institutions.
Possibly because there is no funding available to do so - and no
funding because the results are not patentable and therefore no
financial gain is to be expected. It seems that financial gain is the
only reason people test plants today - the common good and pure
research are perhaps a thing of the past!?

The reason we need these tests done is not really to prove
that the plant remedies work (everyone who uses them knows that
they work, and the empirical evidence is overwhelmingly positive,
usually well documented, and often ancient) - but in order for the
clinics to use them with the blessing of the medical boards approval,
they need to be able to point to scientific tests and their successful
results, carried out by a recognised research institution!

To pick up on a previous message to the forum - I would like to
agree with Dr Seth Seroka, and say that perhaps voicing these
concerns loud and clear is one way to begin to address the problem.
The Phytomedica forum gives everyone the right to do this and be
read by everyone else on the listserver.

I would like to know if the best and most relevant of the views &
opinions expressed on the Phytomedica forum are ever passed
along, collated, and condensed in some way with the idea of a
publication, or as documents or even emails to decision makers in
Health, Research and Government worldwide? Perhaps we need a
list of addresses we could use to do this ourselves!?

Reading the plethora of often conflicting documents and
information regarding Intellectual Property Rights and Genetic
Resource Rights - it seems to me that whatever happens and
however much is said and written and legislated - basically the
resources and Indigenous Knowledge of those who traditionally use
and know their plants but are poor and usually not Western
educated, but live in areas of great biodiversity - is to be "handed
over/sold" to those who do have lots of money and modern
Western technology, but have historically ruined their biodiversity
and usually completely overlooked and ridiculed any of the
Indigenous Knowledge they themselves might have or have had!

Whether the Knowledge or the Genetic Resources are to be sold for
money or in exchange for "equitable agreements" or compensation
of any sort - they are still "taken" and when "developed" will
invariably be too expensive for the original owners to ever afford,
or most likely completely useless and irrelevant to them.

Any form of compensation or "payment" is almost invariably going
to change the way of life, culture, balance of power, and certainly
affect biodiversity and the balance of the environment - and coming
from the "modern Western" world these changes are likely to be
consumerist and Western oriented, doing further damage to
traditional ways of life and culture.

The challenge as I see it is to think completely differently and from a
new viewpoint - look at what is really valuable, in the long term, to
everyone - for their health, their culture, their soul, and especially to
the earth and its immensely fragile and interlocking systems of
plants and animals.

I do not think we are on the right track at the moment, but sincerely
hope and believe there is one, and that it has to be found soon!

Regards, Yvette van Wijk



writing on behalf of:
The Garden Route Botanical Garden Trust & Southern Cape Herbarium - NPO (nonprofit organisation)
- situated in the Moriarty Environmental Centre, 49 Caledon Street, George
Tel/Fax: 044-8501135 Email: yvwijk@pixie.co.za

incorporating

BEEP (Botanical & Environmental Education Project)

IMITHI a project researching traditional medicinal plant use and working with local communities and clinics.

Please visit us at the Herbarium and see the Garden with
its Aids Garden of Hope as well as the Medicnal Plant Mound in process of being
planted.

------------------
Dear Yvette,
I am glad that you are interested in the 'validation' of traditional
remedies. In fact I have a Project going on precisely the same area. I
have been validating the utilisation of herbal remedies as it is used by
the lay people of Mauritius. We have got some very interesting results
and confirms the utilisation of so many of these herbal remedies.
Regards,
Ameenah Gurib-Fakim.


Yvette van Wijk wrote:

Hide message history
>To anyone who can help with advice or recommend S A contacts,
>
>I would very much like to ask anyone in the Phytomedica group if
>there is anyone in South Africa who could help us with testing our
>IMITHI remedies AS THEY ARE for efficacy - as antibacterial,
>antifungal and also anti-inflammatory. OR if anyone else has
>managed to get tests done with whole plant remedies.
>
>It does not seem relevant to test the individual plant ingredients in
>the conventional Western microbiological way by separating,
>using various solvents and drying methods, crushing, centrifuging
>etc. etc. to isolate single chemical components which might have
>these actions.

Greetings to the Group.

The use of herbs as medicine is a global practice. Today according to
the WHO ... 80% of the global population use them as primary health
care. Not so very long ago the figure was 100%. Herbs are literally
the Mother of all Medicine.

The earliest evidence that we have to support that view was the
discovery of a 60,000 year old burial site in Northern Iraq with a
beautiful and evocative name, 'Shanidar'. Surrounding the remains,
and in the dust they found pollen from 8 genra ( A group of the same
type but differing variety) of herbs from the Angiospermae (Flowering
Plants) All of them belong to the species that are still in use as
medicines today.

Plants can indeed be lethal. They were the favourite weapon of
the 'Borgia's' but they can also be healing and nutritive. So that
their awsome power is also benign.

In one herb there is more force and power
than is to be found in all the folders that are read in high college
and which are not fated to live long.

Paracelsus 1493 - 1541.

Herbs elicit every known pharmacological response. This is common
sense because at the molecular level ( a grouping of two or even
trillions of atoms) the whole world in its fecundity is one giant
macromolecule.

In order for it to all hang together, the individual molecules must
mesh with each other. The flowering plants were the Pro-Consul of
mankind. Accordingly our molecular structure in many ways resemble
that of the plants.

It is now understood that plants have muscles; to be sure they are
not constructed like the human muscle but nature has used the same
principle and the same, or similar chemical shapes to produce
movement. Muscle contraction in our specie involves the union of two
proteins called actin and myosin.

An experiment was carried out whereby actin was extracted from a
fungus and added to human myosin. They worked together perfectly; and
when the herbs magnesium eye is aligned with its solar deity, it uses
opsin and carotenoids to see, they are also essential for human
vision; the herbs also use the same nerve transmitter as we do
(acetylcholine) to pass the message.

Such things should not surprise, for we use plant derived hormones
and amino acids and we use plant derived chemical shapes to produce
new shapes. Indoleatic acid or auxin is very similar to the brain
chemical serotonin.

There are various fragments of materia medica from the ancient
Babylonian and Egyptian eras. Examination of the medical recipes show
a fine grasp of the knowledge required of a sophisticated system of
medicine, it cannot be simply brushed aside as magical mumbo jumbo.
Some of the recipes contained animal and insect parts, while others
contained faeces from various sources.

In the past it has been the trend in orthodox medical circles to
dismiss such formulations as gutter or sewer pharmacy, while ignoring
the obvious parallel with modern Sera and vaccines. However, today a
more enlightened interpretation of the evidence is steadily gaining
ground.

"So also the ancient idea of urine and other secretions as drugs
might easily be written off as primitive superstition if we did not
know that it led by rational if quasi-empirical trains of thought
combined with the use of chemical techniques originally developed for
quite different purposes, to the preparation of the steroid and
protein hormones many centuries before the time of experimental
endocrinology and biochemistry."

Doctor Joseph Needham
`Science and Civilisation in China'.
Vol. 5 Chapter 15 Cambridge.

The most famous of the Egyptian medical writing, is the so
called `Ebers' papyrus, which has been dated C 1550 BC, i.e., almost
3,500 years old, therefore we must avoid the trap of confusing
technology with intelligence, or considering scientific theory to be
superior to empirical knowledge, because clearly it is not.

Science does not know how to make living molecules, it must borrow
from nature. Analysis of many different herbs has revealed the fact,
that all of the herbs individual secondary compounds (they elecit the
pharmacologic response from the body) has a distinct reaction in its
own right, in exactly the same way as the Pharmacy single compound
tablet.

A better understanding of this may be had by going to my web page and
reading the article called the 'Foxglove Foxtrot'

Each of those individual chemical entities either modify, by
assisting the major chemical (which in the case of Foxglove is
Digitalis) Or they lessen its effect. Or they will correct a problem
engendered by another chemical entity which is also part of the
spectrum.

The subtle power of nature is dazzling. She balances many hundreds of
chemical compounds to produce a specific response within the human
organism. Such Alchemy is undreamed of by Science. In other words
they cannot do it ... they are chemical childlike dummies when faced
with such astounding complexity.

Their answer is a single or double compound drug. A molecular copy of
a chemical which has had stripped from it all of the natural safety
barriers that nature built into that chemical. That is why isolated
chemical entties can have such disasterous effects.

Substances such as cocaine, morphine, heroin etc are man made
isolated chemicals from a plant of which all of the safety barriers
have been stripped away. Hence they can be lethal. However because
these substances cannot be patented there is no money to be made. So
an attempt is made to produce a synthetic analog (mirror image
molecule) they cannot produce a natural molecule. The mirror image
(dead) can then be patented. In addition they can also snip pieces
off or add to a natural molecule in order to gain a patent. The
results of that human disaster are all around us.

The duplicity and cupidity of the Pharmaceutical Companies is now
legendary. Even the Doctors have fell for it. they all know on which
side their bread is buttered.

In the years 1993 and 1998, studies were published, that estimated
the number of deaths in the USA that were attributable to the medical
system. The figures are as follows;

12 000 deaths a year from unnecessary surgery
7 000 deaths a year from medication errors in hospitals
20 000 deaths a year from other errors in hospitals
80 000 deaths a year from infections acquired in hospitals
106 000 deaths a year from non-error, adverse effects of medications

These 225 000 deaths a year in the United States, represent third
place in the mortality stakes. Heart disease, is in first place, with
Cancer in second. Heart disease, Cancer and Iatrogenic (Physician
caused) disease is out stripping our capacity to deal with it. It is
increasing rapidly, on an annual basis.
Source of figures : Starfield B. JAMA 2000, 284, 483.

The sort of problems listed are not just confined to the prescription
only drugs. The over the counter (OTC's) drugs and pharmacy only
medications (POM's) are generally considered to be safe and yet, the
ubiquitous Aspirin is estimated to be responsible for around 5% of
fatal poisonings each year. The much used anti-inflammatories,
antacids and laxatives are estimated to account for 20% of all drug
related hospital admissions.

The G.P. and MD reporting system for adverse drug reactions is
voluntary. The G.P. is expected to exercise `clinical judgement' and
a patients' report of side-effects is anecdotal, and per se not
considered to be reliable. Accordingly, the Doctors decision to
report or not, is all too often based on a subjective criterion, e.g.
he/she is neurotic, hysterical, hypochondriac, etc. It may well,
equally be ignored because of sheer pressure of work and unwilling to
take on more. More sinister is that they have made a disasterous
mistake. How many deaths due to side effects have not been reported ?

The major point to be made is, that many of the drugs implicated in
fatalities and extreme reactions, had been on the market for a number
of years, and some for decades, before being withdrawn. Given the
evidence surrounding the synthetic and semi-synthetic drugs, the
problem is obviously being under reported, and must only represent a
small percentage of the total deaths and maiming's in any one year.

The World Health Organisation has estimated fully 80% of the world
population use herbal medicine. Therefore 20% must use Pharmaceutical
sourced medicines.

Therefore a rough figure is that 1 billion people globally use
Western style medicine. Therefore even the under reported figures
from the USA (Pop. 252 million) represent that fully 5.67% of the
general public are killed by the Pharmaceutical and Medical
fraternity in the USA.

If we extrapolate that 5.67% on the basis of 1 billion legal drug
users on a worldwide basis then the death toll annually is 56 million
7 hundred thousand.

Never in our recorded history has the human race ever faced such a
carnage and slaughter. To this we must also add the problems of the
man made virus's such as AIDS and Ebola. I feel that there is
sufficient evidence to warrant a real enquiry into how these mutant
entities arrived in Africa and other hotspots around the world. The
official line is to blame the victim. These is how the power brokers
do it, from the most petty little health official up to the real
power brokers.

This sort of truth hardly ever finds its way into the consciousness
of the victims. It is carefully concealed or where it cannot be any
longer concealed, then the truth is cloaked in self serving $10 words.

All of this could be changed but it will not be without some direct
and positive action from the peasantry. All it takes is to withdraw
your support from this monsterous and cancerous system.

Start with the Universities who have close ties with the
Pharmaceutical companies, because it is from there that the bacillus
plague issues forth to wreak its damage in the form of brainwashed
clones who have a high sense of their own importance.

We have already seen that Pfizer fresh from the killings in Nigeria
are now in New Zealand and up to the same game with Auckland
University and the Government Health Department. These are our
children that they are experimenting on.

The Government will not protect us if there is a dollar to be made.
They are spraying West Aucklanders and deliberately refuse to reveal
what they are spraying. Draw your own conclusions.

One death from a natural product, and the weasels emerge from their
lair in the form of Pharmaceutical, Medical and Government Renta
crowd that are making money from the system.

But they do not tell you about the constant stream of bodies from the
back doors of Hospitals in the early hours of the morning. The
Undertakers are doing a roaring business. These victims are just a
few pellets of the medical excreta. Remember 56 million deaths from
Iatrogenic Disease in one year, and this figure is steadily growing.

(1) "Iatrogenic medicine reinforces a morbid society, in which social
control of the population by the medical system, turns into economic
activity."

(2) "The malignant spread of medicine .... turns mutual care and self-
medication into misdemeanors and felonies."

(3) "The divorce between medicine and morality has been defended on
the ground that medical categories, unlike those of law and religion,
rest on scientific foundations exempt from moral values."

Ivan Illich
Medical Nemesis

Those that legally push Ritalin and other dangerous drugs need to
understand that 40% of the children in the USA are now on some kind
of drugs.

What happens there, will happen at a place near you in a very short
time. Even if all the children were all found to be needing such
rubbish, then it is a very prominent marker.

Nature is telling us something. We as a specie are sick. This
sickness has come from the minds of those that support such a bizzare
view of the human body.

That in itself is a form of mental sickness. The time line, of human
experimentation is a clear indicator that this mental sickness has
turned into a Psychopathic myopia.

It is a time for a change of Medical Regime. The power brokers guilt
is now too large to be concealed. That is why these money driven
blots on the face of humanity are trying to gain control of the
natural medicines market. If they do then 80% of the world population
will be disenfranchised. Ripped off by the Politicians, Big Business
and the Universities and those things that the universities have
spawned. the way to break this stranglehold on our lives is to go
and take our money elsewhere.

Human Life Versus Plant Life

Human Life Versus Plant Life
By Alan Hamilton
------------------------------

The worldwide revival of interest in traditional medicine is putting unbearable pressure on natural resources as increasing numbers of plants are harvested for their medicinal properties. Regulation is needed before irreversible damage is done.

Godalming, England: For as long as records have existed, people have relied on plants as the principal components of their medicines. Even today many pharmaceutical drugs are isolated directly through modification of chemicals found in plants, or their development has been inspired by the structures and activities of plant compounds.

About three-quarters of the world's population still uses plant-based preparations in primary health care. In richer countries, herbal medicine is rapidly gaining in popularity because of dissatisfaction with the effectiveness of modern medicines and their side-effects. As pathogenic organisms develop resistance to pharmaceutical medicines, urgent efforts are mounted by companies to uncover more secrets of the plant world and new cures for diseases.
Medicinal plants form by far the largest single category of use of biological resources in numbers of species. It is estimated that at least 25,000 of a total of perhaps 250,000 plant species have been used in this way. In Asia, in particular, there are several systems of plant-based medicine based on long-established written pharmacopoeias, representing the accumulated medical wisdom of ancient times. These are the Chinese, the Tibetan, the Ayurvedic system of India and the Unani system of the Islamic world. Unani, in fact, has developed from the medical practices of the Ancient Greeks.

The vast and expanding market for medicinal plants is placing pressure on resources. Unlike the relatively few species of generally cultivated plants used in the manufacture of pharmaceutical drugs, most species used in herbal preparations are collected in the wild. When harvesting is for local use, there is little over-collection, but the scale of modern commercial pressures on medicinal plants is resulting in widespread depletion.

The Himalayas have been stripped of medicinal plants in some places to feed the demands of distant populations. Large quantities of medicinal plants are smuggled from Nepal into India.
The highly prized medicinal tree Warburgia salutaris has become extinct in Zimbabwe through over-harvesting.

The bark of the montane forest tree, Prunus africana, has been removed extensively in Cameroon, Democratic Republic of Congo, Kenya and Madagascar for export to Europe - a trade currently worth US$220 million a year. Prunus collection on Mt Kilum, Cameroon, has resulted in forests being cleared for agriculture, as traditional taboos on forest clearance have been undermined by modern commercial attitudes.

A few medicinal plants, including Prunus africana, are now listed in CITES, the convention that regulates international trade in endangered species. Concern for conservation of medicinal plants is surfacing at local, national and international levels. A list of recommended measures is published as "Guidelines for the Conservation of Medicinal Plants" by the World Health Organisation (WHO), the World Conservation Union-IUCN, and the World Wide Fund For Nature-WWF.

The Medicinal Plants Group of the Species Survival Commission (SSC) of IUCN is attempting to identify the most threatened medicinal plants across the globe. TRAFFIC-Europe is coordinating national surveys in some European countries with the co-operation of the German CITES plants office, WWF-UK, DHKD (the Turkish Society for the Preservation of Nature - a WWF Associate) and other organisations and agencies.

One of the factors considered by the SSC survey is the degree of threat to species according to socio-economic as well as biological criteria. Biologically, criteria include the known abundance of species, their degrees of endemism, their growth-forms (trees being typically less resilient than herbs) and the parts of the plants harvested (i.e. leaf collection is less damaging than root collection). The socio-economic indicators include popularity, current prices and changes in price over time - higher prices can indicate growing scarcity.

However, it is impossible to regulate the harvesting of medicinal plants purely through legal mechanisms. Cultivation of threatened species can be a useful measure to take the pressure off wild populations, especially if accompanied by steps to protect wild plants better.

Whatever the uptake of cultivation locally, it seems certain that commercial collection of many medicinal plants will mainly continue to be from the wild. It is therefore urgent that systems of wild collection are made more sustainable. This must involve local communities who have detailed knowledge of the plants, as their scattered occurrence means many can be surreptitiously collected. This makes effective regulation through agencies, such as forest and park departments prohibitively expensive.

Agreements are needed between communities and the managers of protected areas to secure rights of collection for local communities, while maintaining and, if possible, augmenting resources. To be effective, there must be institutions within the local communities, such as societies of herbalists or forest-user groups, to whom rights of collection are assigned, and who in return are responsible for the sustainable harvest of the medicinal plants.
Little progress has yet been made to put the necessary measures in place. A start has been made in Nepal in the Annapurna Conservation Area. A WWF project has initiated similar work at Shey Phoksundo National Park, also in Nepal, with a People and Plants project, jointly undertaken with UNESCO and the Royal Botanic Gardens, Kew. Here, local communities survey and establish the sustainability of a collection of medicinal plants.

The aim is to promote agreements between the communities and the park allowing use of medicinal plants in return for their conservation. If such an approach can be shown to be effective, then it can be applied elsewhere to safeguard the future of medicinal plants.
*Alan Hamilton is Plant Conservation Officer at WWF International based in Godalming, UK.

PROTECTION AND CONSERVATION OF MEDICINAL PLANTS IN BOTSWANA: THE CASE OF HARPAGOPHYTUM PROCUMBENS.DC1

PROTECTION AND CONSERVATION OF MEDICINAL PLANTS IN BOTSWANA:
THE CASE OF HARPAGOPHYTUM PROCUMBENS.DC1



TEBOGO MALTHARE2



ABSTRACT



Medicinal plants have been the basis of traditional health care, especially in remote areas where modern health facilities were inadequate. The wide spread provision of health facilities in Botswana and the dilution of local traditions with foreign ones have in the past resulted in a reduction in the use of traditional medicines. The discovery of therapeutic prowess of medicinal plants such as grapple has once again picked the popularity of traditional medicines locally and abroad. This paper takes a case of a

well-known and respected medicinal plant, grapples and discusses its traditional utilization and implications on conservation. Information on traditional practices involving the grapple plant was obtained from the rural communities through routine workshops by TL's extension service. The conventional methods of protecting and conserving medicinal plants are also discussed. An overview of institutions and policy issues that are geared towards the protection of medicinal plants is given with some ideas about the possible actions that could be taken to ensure a bright future for medicinal plants and traditional medicines.



INTRODUCTION



The rural communities are the most hard hit by poverty, especially the female headed households. People depend on agricultural activities for food and some form of employment. Agriculture itself is highly unreliable due to poor soils, unpredictable rains and recurrent droughts. Drought relief programmes that are usually brought in to assist the people to survive the scourge are also unreliable as they depend on whether a particular year has been declared a drought year. In an effort to satisfy their needs for alternative sources of livelihoods the rural people turn to their immediate environment for free natural resources.



The environment of Botswana hosts an impressive diversity and abundance of wild plants that are useful as food, medicines, crafts etc. The words 'veld products' are often used to describe all these plants. The utilization of veld products is usually in the form of harvesting in the wild and selling to urban and peri-urban dwellers. The commercialization of wild plants, including medicinal, is believed to compromise their conservation. Depletion of some plants has been observed in areas where commercial exploitation has been going on for a long time.



The harvesting and utilization of medicinal plants is at times haphazard since they can be obtained from communal areas at will. The depletion of these resources can be attributed to too much harvesting pressure as well as negligent harvesting practices. The responsibility of protecting medicinal plants as well as other indigenous plants lies primarily with the government. The government cannot possibly make people responsible for their own resources if they themselves do not feel that way. Matters relating to medicinal plants cut across various ministries within government. Medicinal plants do occupy a small part of natural resources and they are sometimes referred to only as 'other plants'.



Information on the availability and distribution of medicinal plants is not documented. There have not been efforts to design means of collecting indigenous knowledge about medicinal plants from various sources. Traditional healers are often accused of being secretive about the medicinal plants that they know of. At the same time some argue that the doctors have ethics to follow inorder to protect their practice.



Following the observed depletion of grapple the Government of Botswana (GoB) declared the plant protected only to be harvested by permit holders. This strategy seemed not to be very effective as the resources continued to dwindle. The strategy certainly needed support from the resource users and stakeholders like NGOs.



Thusano Lefatsheng (TL) was found in 1984 with the aim of assisting the rural communities to sustainably utilize their natural resources for their livelihood. TL views domestication of veld resources like medicinal plants as being one viable solution to the problem of over-exploitation. TL hopes to achieve this by developing sustainable techniques for the cultivation at home and harvesting them in the wild and extending these to rural communities. TL takes on board those plant species used for food and medicinal purposes (veld products) that have also been identified as having commercial potential. TL is currently working on the domestication of grapple (Harpagophytum procumbens, DC), Lippia javanica, Lippia scaberrima, Artemisia affra and several indigenous fruits and trees.



MEDICINAL PROPERTIES OF THE GRAPPLE PLANT

(HARPAGOPHYTUM PROCUMBENS, DC)



The grapple plant is also known as the Kalahari Devil's Claw and Sengaprile in Setswana, the national language of Botswana. The Secondary roots of the plant have been used in traditional medicine in Botswana for a long time as a broad spectrum drug against a variety of illnesses including skin cancer, facilitation of smooth delivery, kidney malfunction, etc. It is often taken as a medicine for general good health. There is a rumour among womenfolk that grapple medicine renders birth control pills from clinics ineffective since some women have fallen pregnant after drinking it while on the pill. Grapple is also believed by men to act as an aphrodisiac. This is because it 'cleanses' the blood therefore improving circulation in the body. The roots of grapple are dried and crushed into granules. Boiling water is added and left to infuse overnight. The following morning the liquid is decanted and the resulting portion drunk in three equal portions throughout the day.



In order to understand why the plant was so popular the active ingredients of the drug were isolated in Europe and proven effective against arthritis and rheumatism (Moss, 1981). Pharmacological studies that have been carried out on the extracts of the roots showed that the drug had anti-inflammatory and slightly analgesic effects. Positive results were achieved especially in chronic models of inflammation, for example in formaldehyde-athritis of the white rat.



Following the discovery of the attractive therapeutic properties of grapple the plant became popular in some European countries, particularly Germany, and it has been exported out of Southern Africa for decades. Most of the early exports came from Namibia and alot of it still does. At a later time, Botswana joined the trade, a move which resulted in over-exploitation of the resource. The popularity of grapple has since spread to the Far East where most of the grapple roots exported from Botswana end up.



PROTECTION AND CONSERVATION OF HARPAGOPHYTUM PROCUMBENS, DC



Botswana has a long standing tradition of conserving resources. This may be seen in the large areas of range land that support large livestock populations of the country. In these areas are also various plant species including medicinal ones that are used by the local people for their own needs. Before medicinal plants such as grapple had price tags on them, their protection and/or conservation was ensured, inadvertently by the fact that only traditional healers harvested them. The few number of healers in any given locality meant that the plants were rarely under serious harvesting pressure. The traditional doctors had their own rules of the practice to follow, which in a way did protect the plants they used. Information on what plants were used and how to cure whatever illnesses was not readily given out to those outside the practice.



Traditional doctors have a habit of giving their medicines names that are different from those of the plant from which they obtained them. The prescribed drug made out of grapple roots would be called makgonatsotlhe (that fixes all illnesses or broad spectrum of drug) instead of being called sengaparile. This way only those belonging to the practice and maybe a few more could know what plants were being used as medicines. There are rules also that had to be followed when digging the roots. The harvester should make sure that his/her shadow is not cast above the hole that contains the roots. Otherwise the resulting drug would be rendered useless. The implication of this superstitious "rule of the practice" is not very clear. One could imagine, however, that the harvester needs some light in the hole so that he/she can see whether they is harvesting the right stuff.



In grapple if the parent tuber is cut during harvesting then that lessens the chance of the plant to regenerate in the next season. There are those who believe that there are male and female grapple plants. When they go out harvesting they would look for plants that they believe are male because the females are believed to be weak. Biologically the grapple flowers are bisexual and out crossing. The implication is that a traditional doctor would not go out in the wilderness and harvest every grapple plant he/she comes across and this indeed saves some plants which would produce seeds to propagate others.



The traditional protection and conservation strategies have been effective until the grapple plant was commercialized in the early 1970s. Those who were interested in buying the resource publicized information about the plant and its commercial value. Harvesting pressure on the resources led to its disappearance in certain areas. Ecological studies conducted revealed that the areas most affected were Kgalagadi South and Kweneng West (Sekhwela, 1994). Both these areas were first to harvest and sell the grapple in Botswana. In order to protect the resource the government of Botswana instituted stringent measures. The grapple plant was declared protected only to be harvested with a permit. The harvesting season is also limited from April through June. The legal protection seemed not to have helped much since the resource continued to dwindle (Mbewe, 1993). Harvesters now have to walk long distances on foot or even on donkey backs. At times people have to camp out for a few days in order to increase their harvest.



Thusano Lefatsheng (TL), a local rural development NGO stood up to take the challenge of ensuring the conservation of the grapple plant. TL conservation of medicinal plants from a sustainable utilization perspective. Ecologically friendly harvesting methods have been developed and are continuously tried inorder to protect the wild populations. At the same time optimum agronomic practices are developed, to be extended to the communities to assist them in cultivating the plant at home. This way the pressure of harvesting on the plants in the wild will be reduced as more people take up cultivation. With better management applied on the domestic crop the producers should hope for higher yields and therefore greater economic returns. TL also proposed to the establishment of grapple management areas, which will be a step towards conservation. Such areas will be accessible to researchers and members of the community for purposes of continuing studies on the survival of the plant.



The root system of grapple consists of two types of roots. The primary root which grows vertically downwards into the soil. This is responsible for the regeneration and survival of the plant, hence, the parent tuber. There are several secondary roots that grow laterally from the parent tuber in search for food and water in areas where their parent cannot reach. These are the roots that contain the medicine and on harvesting it is advisable to harvest only the secondary roots and leave the parent one intact. If by mistake the parent tuber is uprooted the harvesters are advised to bury it again and it has a chance of regenerating although it will take long now to produce more secondary tubers. These are the techniques that TL is advising the rural communities about.



Each year before digging can begin, assessments are carried out by the Ministry of Agriculture and Thusano Lefatsheng to ascertain the availability of the resource. After quantitative analysis the Ministry of Agriculture is able to direct the harvesting in terms of the areas and the number of people who can be allowed to harvest. The Ministry of Agriculture is able to suspend harvesting of the grapple in a particular community if there isn't enough resource. The plants are thus given a chance to regenerate and produce more tubers to be harvested in the future.



The interventions by government and NGOS like TL seems not to encourage participation of the resource users in designing the conservation strategies. The assessments do not have input from the people and so is the quota management. The 25kg harvest limited stipulated in the permit is the same per everyone everywhere. The people come in at the end to queue up for harvesting permits. Such strategies could benefit a lot from people's knowledge. There are no procedures to deal with those who harvest too much maybe because the authority does not work with the village leaders.



INSTITUTIONAL AND POLICY FRAMEWORK ANALYSIS



The overall responsibility of protecting and conserving medicinal plants cut across several ministries. The department of Crop Production and Forestry of the Ministry of Agriculture is responsible for the use of agricultural land and forestry resources. The department aims at increasing agricultural production without compromising the protection of the environment. The Agricultural Resources Board (ARB) of the Ministry of Agriculture has authority over the exploitation of the grapple plant and other protected plants. Permits for harvesting grapple are issued by the board and it also makes decisions on where harvesting could be done.



The National Conservation Strategy (NCS) was formed in 1990 and it manifests the GOB'S commitment to sustainable development of a wide range of natural resources. It derives largely from the concerns that many of the natural resources, like some medicinal plants, are under threat of over-exploitation. Some of the conservation goals of the strategy are the protection of endangered species and distribution of incomes and rewards more equitably. The NCS is working towards increasing the effectiveness with which natural resources were used in order to optimize the environmental and economic benefits while minimizing the harmful environmental side effects.



The NCS agency is currently drafting a curriculum for environmental education in Botswana. The chemistry department of the University of Botswana is carrying out research on various medicinal plants including grapple. There is interest within the National Institute of Research and Documentation in the ecology and socio-economics of indigenous plants including medicinal. There is interest as well at the Botswana College of Agriculture in the agronomy and economics of grapple and other indigenous plants that are enlisted for domestication. With more research and documentation on medicinal plants a better understanding from the general public is expected to result in more participation in conservation initiatives.



The national herbarium is entrusted with the responsibility of, among other things, identifying and collecting indigenous plant species. These may be maintained as live specimen in the gardens or as mounted for reservation and records. The National Bio-diversity Authority was established recently after ratification of the convention of Biological diversity. The authority is representation from nearly all government ministries, NGOs, parastatals and the private sector. Its mission is to spearhead the implementation of the conservation in Botswana and to liaise with similar institutions in other countries.



It is encouraging to note that steps are being taken to protect the natural environments. There is danger, however, that the established institutions will pay more attention to seemingly large environmental projects such as water pollution, waste management etc, at the expense of indigenous plant use which are more important at the grassroots level.



The Botswana Dingaka Association was formed in the early nineties as a result of an outcry from traditional healers. The traditional herbalists were not recognized by the government and, in fact, there were cases of publicly campaigning against visiting "witch doctors". The Association was formed to professionalise the practice and to be more transparent towards the general public.



There are several pieces of legislature that the government has put into place in the interest of protection and conservation of natural resources. For the purpose of this paper the ones worth noting include the Tribal Land Act of 1993 which provides for the establishment of the land boards. The boards are charged with the responsibility of allocating land and over-seeing its use in tribal areas. Grazing land in tribal/communal areas are usually overstocked leading to range land degradation.



The Agricultural Resources Conservation Act provides for the conservation of soil, water, vegetation and animals. The Forestry Acts aims at protecting forestry resources. The Forestry Policy that is being drafted by MOA aims at developing sustainable forest management options based on social ecological principles. This policy will recognize medicinal plants as important components of forest systems. The herbage preservation act provides for prevention of veld fires that destroy vegetation.



DISCUSSION



There is a vast resource of knowledge about the indigenous medicinal plants and their uses scattered around different sources. The most important source is the old folks who may of may not be traditional healers or herbalists. Parts of medicinal plants can be seen at every market in urban and peri-urban centres these days. Only the harvesters would know whether these parts were obtained from the mother plants in friendly ways. Traditional healers are now becoming more professional and organized making it easier to approach if only to seek information. It should be recognized, however, that what knowledge these people have did not trickle into their minds in a passive manner but that they made efforts to attain it. Under such circumstances traditional herbalists may not be blamed for being stingy with what they know in relation to medicinal plants and their uses. There is no evidence to suggest that depletion of grapple was there before the plant was commercialized which would have implicated traditional healers.



The case of grapple serves to alert us as to the possible fate of medicinal plants that are currently being exploited, especially for commercial purposes. The steps taken to protect grapple could have been much more effective if they had been more preventive than curative. This case has also shown that legal protection is not an end in itself but only a means to an end. There is tendency for people to look at whatever the law seeks to protect as belonging to the government and not themselves. This sometimes gives people the pleasure of breaking the law in question just to cheat the government. Decentralization of the controls on the utilization of natural resources could assist in cultivating a sense of ownership and responsibility.



The conservation through domestication approach that is being promoted by TL is based on some critical assumptions. The strategy assumes that the market for indigenous medicinal plants will continue to grow to absorb the products from the producers. Adoption of the strategy by traditional healers would be desirable. Traditional healers are known not to use domesticated plants, or even those that grow near inhabited areas for their work. The strategy is aimed at benefiting the rural communities who may not have the required resources to take up the cultivation of medicinal plants and other veld resources. It is assumed that these people will be able to receive assistance from the government such as that received by the producers of the conventional food crops. The experience at TL is with grapple, a creeping herbaceous plant, and three herbal teas; Lippia javanica, L scaberrima and Artemisia affra. A lot of traditional medicines however are obtained from roots of large trees such as Acaia karoo and Dischrostachys cineria.



The protection and conservation of medicinal plants does not take high priority on the agenda for natural resources management. Government programmes gives priority to agricultural and wildlife resources. This is mainly due to the identified potential of such resources in contributing positively to national development. On the other hand, it could be that there is so much information about agricultural, forestry and wildlife resources as compared to medicinal plants. This allows programmes to be developed for those systems that are better understood. The area of medicinal plants is left alone as a niche for traditional doctors. Institutions that are involved with medicinal plants such as the national herbarium do not receive as much support as the others do.



The forestry policy in draft promises in specific terms to look into the issues of protection in conservation of medicinal plants. It is important that the policy be made up of ideas from the people who use the resources. The policy should provide for the formulation of strategies that puts the control of resources into the hands of the communities.



CONCLUSIONS AND RECOMMENDATIONS



The value of traditional medicines is gaining recognition in conventional health care locally and abroad. The markets created for medicinal plants around the world results in high harvesting pressure on the plants, thereby compromising their ability to regenerate hence resource depletion. The future of medicinal plants in Botswana depends on positive steps being taken to protect and conserve the resources before it is too late. The case of grapple bears testimony to this. There is alot that could be learnt from the traditional methods of conserving resources of great value if only strategies for obtaining such knowledge could be investigated and put to work.



The value of knowledge that indigenous people like herbalists and community leaders have needs to be recognized and perhaps rewarded by those who benefit from it one way or the other. Institutional reforms are necessary in order that conservation problems of medicinal plants can be addressed more directly instead of dealing with them as a single paragraph in a whole book. Emergence of institutions like the Bio-diversity Authority and the Botswana Dingaka Association should be strengthened to adequately deal with the issues that are important at grassroots level. The capacity of learning institutions like the University of Botswana, the National Institute for Research and Documentation, the Botswana college of Agriculture and the Institute of Health Sciences should be increased so as to take more on board in terms of research and documentation on medicinal plants and their uses.







REFERENCES



Mbewe, M.N., (1992) 'The Distribution, Utilization and Conservation of Some Under-Utilized Plant Genetic Resources in Botswana'. Paper presented at National Workshop on Plant Genetic Resources, Gaborone Sun, Gaborone, Botswana. June 23 - 26, 1992



Mbewe, M.N., (1993) Conservation and Utilization of Food and Medicinal Plants in Botswana. In de Boef, W., Amanor, K., Wellard, K., and Bennington, A (eds) cultivating knowledge. CGN/ODI/WAU/IT Publications. London, UK.



Moss, H. And Taylor, F.W., (1981) The potential for commercial utilisation of veld products. Ministry of Commerce and Industry of Botswana. Government Printer, Gaborone, Botswana.



Sekhwela, M.B.M., (1994) Grapple Plants (Harpagophytum procumbens, DC). Resource Potential and Management Studies. Final Report of the Consultancy for TL and NRMP.



Taylor, F.W., (1981) Commercial Utilization of Indigenous Plants in Botswana in Wickens, G.E., Goodin, J.R. and Field, D.V. (eds) Plants for Arid Lands.




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